Name: James Rogers
Research interests or projects:
Dysfunction of the immune system can occur through a variety of mechanisms. Implicated in dysfunction associated with autoimmune disorders are a variety of environmental factors. Focusing on Multiple Sclerosis (MS) we can implicate factors such as Vitamin D exposure in a effort to discern regional effects associated with higher disease prevalence. Further examination is required of environmental influences on the immune system in the context of inflammation and MS. My primary research focus is on persistent environmental contaminants where human exposure may lead to dysfunction of immune cell subsets, resulting in aberrant immune responses and enhanced inflammation. We examine these chemicals in the context of increased susceptibility of animals to Experimental Autoimmune Encephalomyelitis, our animals model of MS. We can then dissect the cellular and molecular pathways and alterations which occur as a result of chemical exposure. Further projects in which I am involved include work with potential remyelination therapies in the context of effects of these compounds on the immune system of animals.
Rogers J, Metz LM, Yong VW, Endocrine disrupting chemicals and immune responses:A focus on bisphenol-A and its potential mechanisms, Molecular Immunol 53:421-430, 2013
Camping, Fishing, Outdoors, Guitar.